Dr. Marks has a special interest in sports medicine, arthroscopy and reconstruction of the shoulder and knee. His research activities involve imaging, biomechanics, ultrastructural morphology, and clinical aspects of the cruciate and meniscofemoral ligaments.
He holds grants from the Canadian Institutes of Health Research and the Canadian Arthritis Network for research in predicting factors for developing arthritis in the knee. He is part of the multidisciplinary team studying cytokine and biomarker imaging and outcome measures in patients at risk for developing arthritis.
Dr. Marks is also part of the ProKnee study, which is a multi-institutional research group that spans three Canadian cities: Toronto, Calgary and Montreal. The ProKnee study, the first of its kind in Canada, examines the relationship between risk factors and the progression of osteoarthritis after anterior cruciate ligament injury. Several assessment criteria are used, all of which rely on the meticulous reporting of clinical data from Dr. Marks’ practice. Particularly, mathematical and in vivo models of specific tissue deficits are constructed to approximate the lesions found in patients’ knees.